Mtb32 is a promising tuberculosis antigen for DNA vaccination in pre- and post-exposure mouse models
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چکیده
منابع مشابه
ESAT-6 (EsxA) and TB10.4 (EsxH) Based Vaccines for Pre- and Post-Exposure Tuberculosis Vaccination
The ESX systems from Mycobacterium tuberculosis are responsible for the secretion of highly immunogenic proteins of key importance for bacterial survival and growth. The two prototypic proteins, ESAT-6 (EsxA from ESX-1) and TB10.4 (EsxH from ESX-3) share a lot of characteristics regarding genome organization, size, antigenic properties, and vaccine potential but the two molecules clearly have v...
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ژورنال
عنوان ژورنال: Gene Therapy
سال: 2011
ISSN: 0969-7128,1476-5462
DOI: 10.1038/gt.2011.140